I had an urban garden about that size. I was able to grow all our fruits in the "orchard" on 10 semi-dwarf trees (regular fruit trees grafted onto dwarfing root stock). I had raised beds for intensive planting of vegetables. You can enclosed a raised bed in a mini-greenhouse that sets on top of the bed to extend your growing season, if necessary. Since the lot is a bit small, grow a lot vertically with trellises everywhere. Sprawling crops can all be grown upward, tied to a trellis for support. I've seen people with pumpkin gardens on the roof of their house - uses the space and cools the house in summer. Also, the south-facing exterior wall of the house can be trellised so that you can grow warmth-loving vines - the wall acts like a heat sink as it warms up all day long; then, the heat radiates off the wall after sunset, keeping the plants warm at night.
This kind of garden is a very relaxing location, so include little sitting areas. Keeping "curves" in your pathway design to make the garden more natural looking. Install irrigation pipes underground, if that's how you plan to water.
You can also build portable hen houses that sit on top of the beds that you are fallowing. I never had livestock due to zoning regulations, but if I could, I would have put goats/sheep in the front yard and ducks in a pond in the back corner.
Read books or online about "urban farming" to get ideas that will maximize the use of your space. Also, get to know other gardeners in your area. Gardeners are good friends, plus you can trade tips, surplus food, and favorite seeds.
